New Geography's Why the Great Plains are Great Once Again covers the economic success happening in many of the larger cities and towns in Great Plains.
The article focuses on Fargo, ND, but also talks about the broader upper midwest - which has a very strong economy relative to most of the rest of the U.S.
The midwest is benefiting from strong food, commodity and energy prices. The midwest also did not participate as much in the credit related housing bubble, so the credit bust has not hurt the region as much as other areas. Costs - both living and business - are also much lower than most of the coastal U.S. areas.
But as the article points out, it is not just commodity related industries that are doing well in the Heartland. Technology firms looking for skilled labor and low costs are also starting to thrive in places like Fargo.
I grew up in a small, midwestern farm town and admit to being biased towards the Heartland. It's good to see good things happening there.